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Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy

SIMPLE SUMMARY: Atypical teratoid rhabdoid tumour (ATRT) is an aggressive undifferentiated malignancy of the central nervous system in children. A defining feature of ATRT is the loss of the SMARCB1 gene that is essential for regulating gene expression required for normal developmental processes. We...

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Detalles Bibliográficos
Autores principales: Chong, Wai C., Jayasekara, W. Samantha N., Vaghjiani, Vijesh G., Parackal, Sarah, Sun, Claire, Popovski, Dean, Algar, Elizabeth M., Firestein, Ron, Wood, Paul J., Khan, Sara, Huang, Annie, Ashley, David M., Downie, Peter, Cain, Jason E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534272/
https://www.ncbi.nlm.nih.gov/pubmed/34680294
http://dx.doi.org/10.3390/cancers13205145