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Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy
SIMPLE SUMMARY: Atypical teratoid rhabdoid tumour (ATRT) is an aggressive undifferentiated malignancy of the central nervous system in children. A defining feature of ATRT is the loss of the SMARCB1 gene that is essential for regulating gene expression required for normal developmental processes. We...
Autores principales: | Chong, Wai C., Jayasekara, W. Samantha N., Vaghjiani, Vijesh G., Parackal, Sarah, Sun, Claire, Popovski, Dean, Algar, Elizabeth M., Firestein, Ron, Wood, Paul J., Khan, Sara, Huang, Annie, Ashley, David M., Downie, Peter, Cain, Jason E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534272/ https://www.ncbi.nlm.nih.gov/pubmed/34680294 http://dx.doi.org/10.3390/cancers13205145 |
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