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Targeting Chaperone/Co-Chaperone Interactions with Small Molecules: A Novel Approach to Tackle Neurodegenerative Diseases

The dysfunction of the proteostasis network is a molecular hallmark of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Molecular chaperones are a major component of the proteostasis network and maintain cellular ho...

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Detalles Bibliográficos
Autores principales: Wang, Lisha, Bergkvist, Liza, Kumar, Rajnish, Winblad, Bengt, Pavlov, Pavel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534281/
https://www.ncbi.nlm.nih.gov/pubmed/34685574
http://dx.doi.org/10.3390/cells10102596