HIV-1 Vpr-Induced Proinflammatory Response and Apoptosis Are Mediated through the Sur1-Trpm4 Channel in Astrocytes

Successful treatment of HIV-infected patients with combinational antiretroviral therapies (cART) can now prolong patients’ lives to nearly normal life spans. However, the new challenge faced by many of those HIV-infected patients is chronic neuroinflammation and neurotoxicity that often leads to HIV...

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Detalles Bibliográficos
Autores principales: Li, Ge, Makar, Tapas, Gerzanich, Volodymyr, Kalakonda, Sudhakar, Ivanova, Svetlana, Pereira, Edna F. R., Andharvarapu, Sanketh, Zhang, Jiantao, Simard, J. Marc, Zhao, Richard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534293/
https://www.ncbi.nlm.nih.gov/pubmed/33293383
http://dx.doi.org/10.1128/mBio.02939-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534293/
https://www.ncbi.nlm.nih.gov/pubmed/33293383
http://dx.doi.org/10.1128/mBio.02939-20

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