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Transcriptomic Biomarkers for Tuberculosis: Validation of NPC2 as a Single mRNA Biomarker to Diagnose TB, Predict Disease Progression, and Monitor Treatment Response

External validation in different cohorts is a key step in the translational development of new biomarkers. We previously described three host mRNA whose expression in peripheral blood is significantly higher (NPC2) or lower (DOCK9 and EPHA4) in individuals with TB compared to latent TB infection (LT...

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Detalles Bibliográficos
Autores principales: de Araujo, Leonardo S., Ribeiro-Alves, Marcelo, Wipperman, Matthew F., Vorkas, Charles Kyriakos, Pessler, Frank, Saad, Maria Helena Féres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534371/
https://www.ncbi.nlm.nih.gov/pubmed/34685683
http://dx.doi.org/10.3390/cells10102704