Cargando…
Transcriptomic Biomarkers for Tuberculosis: Validation of NPC2 as a Single mRNA Biomarker to Diagnose TB, Predict Disease Progression, and Monitor Treatment Response
External validation in different cohorts is a key step in the translational development of new biomarkers. We previously described three host mRNA whose expression in peripheral blood is significantly higher (NPC2) or lower (DOCK9 and EPHA4) in individuals with TB compared to latent TB infection (LT...
Autores principales: | de Araujo, Leonardo S., Ribeiro-Alves, Marcelo, Wipperman, Matthew F., Vorkas, Charles Kyriakos, Pessler, Frank, Saad, Maria Helena Féres |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534371/ https://www.ncbi.nlm.nih.gov/pubmed/34685683 http://dx.doi.org/10.3390/cells10102704 |
Ejemplares similares
-
Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood
por: de Araujo, Leonardo S., et al.
Publicado: (2016) -
Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
por: de Araujo, Leonardo Silva, et al.
Publicado: (2019) -
Exploring the value of Mycobacterium tuberculosis modified lipoprotein as a potential biomarker for TB detection in children
por: Yang, Xinxin, et al.
Publicado: (2022) -
RNomic identification and evaluation of npcTB_6715, a non‐protein‐coding RNA gene as a potential biomarker for the detection of Mycobacterium tuberculosis
por: Kanniappan, Priyatharisni, et al.
Publicado: (2017) -
Mycobacterium tuberculosis-specific cytokine biomarkers for the diagnosis of childhood TB in a TB-endemic setting
por: Sudbury, Eva L., et al.
Publicado: (2019)