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The Relevance of SOCS1 Methylation and Epigenetic Therapy in Diverse Cell Populations of Hepatocellular Carcinoma

The suppressor of cytokine signaling 1 (SOCS1) is a tumor suppressor gene found to be hypermethylated in cancers. It is involved in the oncogenic transformation of cirrhotic liver tissues. Here, we investigated the clinical relevance of SOCS1 methylation and modulation upon epigenetic therapy in div...

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Detalles Bibliográficos
Autores principales: Cabral, Loraine Kay D., Reyes, Peter Andrew C., Crocè, Lory S., Tiribelli, Claudio, Sukowati, Caecilia H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534387/
https://www.ncbi.nlm.nih.gov/pubmed/34679523
http://dx.doi.org/10.3390/diagnostics11101825