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‘Off-the-Shelf’ Immunotherapy: Manufacture of CD8(+) T Cells Derived from Hematopoietic Stem Cells

Cellular immunotherapy is revolutionizing cancer treatment. However, autologous transplants are complex, costly, and limited by the number and quality of T cells that can be isolated from and expanded for re-infusion into each patient. This paper demonstrates a stromal support cell-free in vitro met...

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Detalles Bibliográficos
Autores principales: Boyd, Nicholas, Cartledge, Kellie, Cao, Huimin, Evtimov, Vera, Pupovac, Aleta, Trounson, Alan, Boyd, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534391/
https://www.ncbi.nlm.nih.gov/pubmed/34685611
http://dx.doi.org/10.3390/cells10102631