Ion Channel Impairment and Myofilament Ca(2+) Sensitization: Two Parallel Mechanisms Underlying Arrhythmogenesis in Hypertrophic Cardiomyopathy

Life-threatening ventricular arrhythmias are the main clinical burden in patients with hypertrophic cardiomyopathy (HCM), and frequently occur in young patients with mild structural disease. While massive hypertrophy, fibrosis and microvascular ischemia are the main mechanisms underlying sustained r...

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Detalles Bibliográficos
Autores principales: Santini, Lorenzo, Coppini, Raffaele, Cerbai, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534456/
https://www.ncbi.nlm.nih.gov/pubmed/34685769
http://dx.doi.org/10.3390/cells10102789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534456/
https://www.ncbi.nlm.nih.gov/pubmed/34685769
http://dx.doi.org/10.3390/cells10102789

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