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KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease

Neurogenesis decreases in Alzheimer’s disease (AD) patients, suggesting that restoring the normal neurogenic response could be a disease modifying intervention. To study the mechanisms of pathology-induced neuro-regeneration in vertebrate brains, zebrafish is an excellent model due to its extensive...

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Detalles Bibliográficos
Autores principales: Siddiqui, Tohid, Bhattarai, Prabesh, Popova, Stanislava, Cosacak, Mehmet Ilyas, Sariya, Sanjeev, Zhang, Yixin, Mayeux, Richard, Tosto, Giuseppe, Kizil, Caghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534484/
https://www.ncbi.nlm.nih.gov/pubmed/34685728
http://dx.doi.org/10.3390/cells10102748