Cargando…
KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease
Neurogenesis decreases in Alzheimer’s disease (AD) patients, suggesting that restoring the normal neurogenic response could be a disease modifying intervention. To study the mechanisms of pathology-induced neuro-regeneration in vertebrate brains, zebrafish is an excellent model due to its extensive...
Autores principales: | Siddiqui, Tohid, Bhattarai, Prabesh, Popova, Stanislava, Cosacak, Mehmet Ilyas, Sariya, Sanjeev, Zhang, Yixin, Mayeux, Richard, Tosto, Giuseppe, Kizil, Caghan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534484/ https://www.ncbi.nlm.nih.gov/pubmed/34685728 http://dx.doi.org/10.3390/cells10102748 |
Ejemplares similares
-
Alzheimer’s disease, neural stem cells and neurogenesis: cellular phase at single-cell level
por: Cosacak, Mehmet Ilyas, et al.
Publicado: (2019) -
Protocol for Dissection and Dissociation of Zebrafish Telencephalon for Single-Cell Sequencing
por: Cosacak, Mehmet Ilyas, et al.
Publicado: (2020) -
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain
por: Bhattarai, Prabesh, et al.
Publicado: (2020) -
Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease
por: Cosacak, Mehmet Ilyas, et al.
Publicado: (2022) -
GATA3 Promotes the Neural Progenitor State but Not Neurogenesis in 3D Traumatic Injury Model of Primary Human Cortical Astrocytes
por: Celikkaya, Hilal, et al.
Publicado: (2019)