Chemical Genetic Screen in Drosophila Germline Uncovers Small Molecule Drugs That Sensitize Stem Cells to Insult-Induced Apoptosis

Cancer stem cells, in contrast to their more differentiated daughter cells, can endure genotoxic insults, escape apoptosis, and cause tumor recurrence. Understanding how normal adult stem cells survive and go to quiescence may help identify druggable pathways that cancer stem cells have co-opted. In...

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Detalles Bibliográficos
Autores principales: Ishibashi, Julien Roy, Keshri, Riya, Taslim, Tommy Henry, Brewer, Daniel Kennedy, Chan, Tung Ching, Lyons, Scott, McManamen, Anika Marie, Chen, Ashley, Del Castillo, Debra, Ruohola-Baker, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534514/
https://www.ncbi.nlm.nih.gov/pubmed/34685753
http://dx.doi.org/10.3390/cells10102771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534514/
https://www.ncbi.nlm.nih.gov/pubmed/34685753
http://dx.doi.org/10.3390/cells10102771

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