The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells

Patients with prostate cancer (PCa) receiving docetaxel chemotherapy invariably develop chemoresistance. The transcription co-activator lens epithelium-derived growth factor p75 (LEDGF/p75), also known as DFS70 and PSIP1, is upregulated in several human cancers, including PCa and promotes resistance...

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Detalles Bibliográficos
Autores principales: Ortiz-Hernandez, Greisha L., Sanchez-Hernandez, Evelyn S., Ochoa, Pedro T., Elix, Catherine C., Alkashgari, Hossam R., McMullen, James R. W., Soto, Ubaldo, Martinez, Shannalee R., Diaz Osterman, Carlos J., Mahler, Michael, Roy, Sourav, Casiano, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534522/
https://www.ncbi.nlm.nih.gov/pubmed/34685704
http://dx.doi.org/10.3390/cells10102723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534522/
https://www.ncbi.nlm.nih.gov/pubmed/34685704
http://dx.doi.org/10.3390/cells10102723

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