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A Cardiac Mitochondrial FGFR1 Mediates the Antithetical Effects of FGF2 Isoforms on Permeability Transition

Mitochondria, abundant organelles in high energy demand cells such as cardiomyocytes, can determine cell death or survival by regulating the opening of mitochondrial permeability transition pore, mPTP. We addressed the hypothesis that the growth factor FGF2, known to reside in intracellular location...

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Detalles Bibliográficos
Autores principales: Srisakuldee, Wattamon, Nickel, Barbara E., Fandrich, Robert R., Zhang, Feixong, Pasumarthi, Kishore B. S., Kardami, Elissavet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534529/
https://www.ncbi.nlm.nih.gov/pubmed/34685716
http://dx.doi.org/10.3390/cells10102735