Cargando…

Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions

Here, we have unveiled the effects of cycloastragenol against Aβ (Amyloid-beta)-induced oxidative stress, neurogenic dysfunction, activated mitogen-activated protein (MAP) kinases, and mitochondrial apoptosis in an Aβ-induced mouse model of Alzheimer’s disease (AD). The Aβ-induced mouse model was de...

Descripción completa

Detalles Bibliográficos
Autores principales: Ikram, Muhammad, Jo, Myeung Hoon, Choe, Kyonghwan, Khan, Amjad, Ahmad, Sareer, Saeed, Kamran, Kim, Min Woo, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534642/
https://www.ncbi.nlm.nih.gov/pubmed/34685699
http://dx.doi.org/10.3390/cells10102719