Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference

Exposure to ubiquitous endocrine-disrupting chemicals (EDCs) is a major public health concern. We analyzed the physiological impact of the EDC, di-2-ethylhexyl phthalate (DEHP), and found that its metabolite, mono-2-ethylhexyl phthalate (MEHP), had significant adverse effects on myeloid hematopoiesi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaiser, Lars, Quint, Isabel, Csuk, René, Jung, Manfred, Deigner, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534767/
https://www.ncbi.nlm.nih.gov/pubmed/34685682
http://dx.doi.org/10.3390/cells10102703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534767/
https://www.ncbi.nlm.nih.gov/pubmed/34685682
http://dx.doi.org/10.3390/cells10102703

Ejemplares similares