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Modeling Hypoxic Stress In Vitro Using Human Embryonic Stem Cells Derived Cardiomyocytes Matured by FGF4 and Ascorbic Acid Treatment

Mature cardiomyocytes (CMs) obtained from human pluripotent stem cells (hPSCs) have been required for more accurate in vitro modeling of adult-onset cardiac disease and drug discovery. Here, we found that FGF4 and ascorbic acid (AA) induce differentiation of BG01 human embryonic stem cell–cardiogeni...

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Detalles Bibliográficos
Autores principales: Choi, Seung-Cheol, Seo, Ha-Rim, Cui, Long-Hui, Song, Myeong-Hwa, Noh, Ji-Min, Kim, Kyung-Seob, Choi, Ji-Hyun, Kim, Jong-Ho, Park, Chi-Yeon, Joo, Hyung Joon, Hong, Soon Jun, Ko, Tae Hee, Choi, Jong-Il, Kim, Hyo Jin, Kim, Jong-Hoon, Paek, Se-Hwan, Park, Ji-Na, Kim, Dong-Hyung, Jang, Yongjun, Park, Yongdoo, Lim, Do-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534799/
https://www.ncbi.nlm.nih.gov/pubmed/34685725
http://dx.doi.org/10.3390/cells10102741