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Emerging Roles of N6-Methyladenosine Modification in Neurodevelopment and Neurodegeneration
N6-methyladenosine (m(6)A), the most abundant modification in messenger RNAs (mRNAs), is deposited by methyltransferases (“writers”) Mettl3 and Mettl14 and erased by demethylases (“erasers”) Fto and Alkbh5. m(6)A can be recognized by m(6)A-binding proteins (“readers”), such as Yth domain family prot...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534826/ https://www.ncbi.nlm.nih.gov/pubmed/34685675 http://dx.doi.org/10.3390/cells10102694 |