Regulation of Tumor Metabolism and Extracellular Acidosis by the TIMP-10–CD63 Axis in Breast Carcinoma

A hallmark of malignant solid tumor is extracellular acidification coupled with metabolic switch to aerobic glycolysis. Using the human MCF10A progression model of breast cancer, we show that glycolytic switch and extracellular acidosis in aggressive cancer cells correlate with increased expression...

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Detalles Bibliográficos
Autores principales: Najy, Abdo J., Jung, Young-Suk, Kim, Seongho, Fridman, Rafael, Kim, Hyeong-Reh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535136/
https://www.ncbi.nlm.nih.gov/pubmed/34685701
http://dx.doi.org/10.3390/cells10102721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535136/
https://www.ncbi.nlm.nih.gov/pubmed/34685701
http://dx.doi.org/10.3390/cells10102721

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