Cargando…
Regulation of Tumor Metabolism and Extracellular Acidosis by the TIMP-10–CD63 Axis in Breast Carcinoma
A hallmark of malignant solid tumor is extracellular acidification coupled with metabolic switch to aerobic glycolysis. Using the human MCF10A progression model of breast cancer, we show that glycolytic switch and extracellular acidosis in aggressive cancer cells correlate with increased expression...
Autores principales: | Najy, Abdo J., Jung, Young-Suk, Kim, Seongho, Fridman, Rafael, Kim, Hyeong-Reh C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535136/ https://www.ncbi.nlm.nih.gov/pubmed/34685701 http://dx.doi.org/10.3390/cells10102721 |
Ejemplares similares
-
Establishment of Structure-Function Relationship of Tissue Inhibitor of Metalloproteinase-1 for Its Interaction with CD63: Implication for Cancer Therapy
por: Warner, Richard B., et al.
Publicado: (2020) -
E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR
por: Pham, Tri, et al.
Publicado: (2022) -
TIMP-1 Induces an EMT-Like Phenotypic Conversion in MDCK Cells Independent of Its MMP-Inhibitory Domain
por: Jung, Young Suk, et al.
Publicado: (2012) -
The production of recombinant platelet‐derived growth factor D using the second generation modified vaccinia Ankara viral system
por: Najy, Abdo J., et al.
Publicado: (2022) -
Photodynamic Therapy as a Potent Radiosensitizer in Head and Neck Squamous Cell Carcinoma
por: Cho, Won Jin, et al.
Publicado: (2021)