Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action

Chagas disease is a neglected illness caused by Trypanosoma cruzi and its treatment is done only with two drugs, nifurtimox and benznidazole. However, both drugs are ineffective in the chronic phase, in addition to causing serious side effects. This context of therapeutic limitation justifies the co...

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Detalles Bibliográficos
Autores principales: Trindade, Joana D’Arc S., Freire-de-Lima, Célio Geraldo, Côrte-Real, Suzana, Decote-Ricardo, Debora, Freire de Lima, Marco Edilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535186/
https://www.ncbi.nlm.nih.gov/pubmed/34679091
http://dx.doi.org/10.1371/journal.pone.0258292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535186/
https://www.ncbi.nlm.nih.gov/pubmed/34679091
http://dx.doi.org/10.1371/journal.pone.0258292

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