An Investigation of the Role of Common and Rare Variants in a Large Italian Multiplex Family of Multiple Sclerosis Patients

Known multiple sclerosis (MS) susceptibility variants can only explain half of the disease’s estimated heritability, whereas low-frequency and rare variants may partly account for the missing heritability. Thus, here we sought to determine the occurrence of rare functional variants in a large Italia...

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Detalles Bibliográficos
Autores principales: Barizzone, Nadia, Cagliani, Rachele, Basagni, Chiara, Clarelli, Ferdinando, Mendozzi, Laura, Agliardi, Cristina, Forni, Diego, Tosi, Martina, Mascia, Elisabetta, Favero, Francesco, Corà, Davide, Corrado, Lucia, Sorosina, Melissa, Esposito, Federica, Zuccalà, Miriam, Vecchio, Domizia, Liguori, Maria, Comi, Cristoforo, Comi, Giancarlo, Martinelli, Vittorio, Filippi, Massimo, Leone, Maurizio, Martinelli-Boneschi, Filippo, Caputo, Domenico, Sironi, Manuela, Guerini, Franca Rosa, D’Alfonso, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535321/
https://www.ncbi.nlm.nih.gov/pubmed/34681001
http://dx.doi.org/10.3390/genes12101607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535321/
https://www.ncbi.nlm.nih.gov/pubmed/34681001
http://dx.doi.org/10.3390/genes12101607

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