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Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach

PIM1, is a serine/threonine proto-oncogene kinase, involved in many biological functions, including cell survival, proliferation, and differentiation, thus play a key role in oncogenesis. It plays a crucial role in the onset and progression of various hematopoietic and non-hematopoietic malignancies...

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Detalles Bibliográficos
Autores principales: Shafie, Alaa, Khan, Shama, Batra, Sagar, Anjum, Farah, Mohammad, Taj, Alam, Shoaib, Yadav, Dharmendra Kumar, Islam, Asimul, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535467/
https://www.ncbi.nlm.nih.gov/pubmed/34679086
http://dx.doi.org/10.1371/journal.pone.0258929