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Influence of Renal Impairment and Genetic Subtypes on Warfarin Control in Japanese Patients

The genotypes of vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) can influence therapeutic warfarin doses. Conversely, nongenetic factors, especially renal function, are associated with warfarin maintenance doses; however, the optimal algorithm for considering genes a...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomotaka, Ihara, Masafumi, Fukuma, Kazuki, Yamamoto, Haruko, Washida, Kazuo, Kimura, Shunsuke, Kada, Akiko, Miyata, Shigeki, Miyata, Toshiyuki, Nagatsuka, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535514/
https://www.ncbi.nlm.nih.gov/pubmed/34680932
http://dx.doi.org/10.3390/genes12101537