Primary Ciliogenesis by 2-Isopropylmalic Acid Prevents PM2.5-Induced Inflammatory Response and MMP-1 Activation in Human Dermal Fibroblasts and a 3-D-Skin Model

Particulate matters (PMs) increase oxidative stress and inflammatory response in different tissues. PMs disrupt the formation of primary cilia in various skin cells, including keratinocytes and melanocytes. In this study, we found that 2-isopropylmalic acid (2-IPMA) promoted primary ciliogenesis and...

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Detalles Bibliográficos
Autores principales: Bae, Ji-Eun, Min, Daejin, Choi, Ji Yeon, Choi, Hyunjung, Kim, Joon Bum, Park, Na Yeon, Jo, Doo Sin, Kim, Yong Hwan, Na, Hye-Won, Kim, Yoon Jae, Kim, Eun Sung, Kim, Hyoung-June, Cho, Dong-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535518/
https://www.ncbi.nlm.nih.gov/pubmed/34681602
http://dx.doi.org/10.3390/ijms222010941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535518/
https://www.ncbi.nlm.nih.gov/pubmed/34681602
http://dx.doi.org/10.3390/ijms222010941

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