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Modulation of Global Gene Expression by Aneuploidy and CNV of Dosage Sensitive Regulatory Genes

Aneuploidy, which disrupts the genetic balance due to partial genome dosage changes, is usually more detrimental than euploidy variation. To investigate the modulation of gene expression in aneuploidy, we analyzed the transcriptome sequencing data of autosomal and sex chromosome trisomy in Drosophil...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Wang, Ruixue, Huang, Cheng, Zhang, Ludan, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535535/
https://www.ncbi.nlm.nih.gov/pubmed/34681000
http://dx.doi.org/10.3390/genes12101606