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Selective Activation of Endoplasmic Reticulum Stress by Reactive-Oxygen-Species-Mediated Ochratoxin A-Induced Apoptosis in Tubular Epithelial Cells

Ochratoxin A (OTA), one of the major food-borne mycotoxins, impacts the health of humans and livestock by contaminating food and feed. However, the underlying mechanism of OTA nephrotoxicity remains unknown. This study demonstrated that OTA induced apoptosis through selective endoplasmic reticulum (...

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Detalles Bibliográficos
Autores principales: Khoi, Chong-Sun, Lin, Yu-Wen, Chen, Jia-Huang, Liu, Biing-Hui, Lin, Tzu-Yu, Hung, Kuan-Yu, Chiang, Chih-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535626/
https://www.ncbi.nlm.nih.gov/pubmed/34681610
http://dx.doi.org/10.3390/ijms222010951