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RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis

Mammalian chromosomes are three-dimensional entities shaped by converging and opposing forces. Mitotic cell division induces marked chromosome condensation, but following reentry into the G(1) phase of the cell cycle, chromosomes reestablish their interphase organization. Here, we tested the role of...

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Detalles Bibliográficos
Autores principales: Zhang, Shu, Übelmesser, Nadine, Josipovic, Natasa, Forte, Giada, Slotman, Johan A., Chiang, Michael, Gothe, Henrike Johanna, Gusmao, Eduardo Gade, Becker, Christian, Altmüller, Janine, Houtsmuller, Adriaan B., Roukos, Vassilis, Wendt, Kerstin S., Marenduzzo, Davide, Papantonis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535795/
https://www.ncbi.nlm.nih.gov/pubmed/34678064
http://dx.doi.org/10.1126/sciadv.abg8205