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Neurodegenerative processes accelerated by protein malnutrition and decelerated by essential amino acids in a tauopathy mouse model

Protein malnutrition is epidemiologically suggested as a potential risk factor for senile dementia, although molecular mechanisms linking dietary proteins and amino acids to neurodegeneration remain unknown. Here, we show that a low-protein diet resulted in down-regulated expression of synaptic comp...

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Detalles Bibliográficos
Autores principales: Sato, Hideaki, Takado, Yuhei, Toyoda, Sakiko, Tsukamoto-Yasui, Masako, Minatohara, Keiichiro, Takuwa, Hiroyuki, Urushihata, Takuya, Takahashi, Manami, Shimojo, Masafumi, Ono, Maiko, Maeda, Jun, Orihara, Asumi, Sahara, Naruhiko, Aoki, Ichio, Karakawa, Sachise, Isokawa, Muneki, Kawasaki, Noriko, Kawasaki, Mika, Ueno, Satoko, Kanda, Mayuka, Nishimura, Mai, Suzuki, Katsuya, Mitsui, Akira, Nagao, Kenji, Kitamura, Akihiko, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535828/
https://www.ncbi.nlm.nih.gov/pubmed/34678069
http://dx.doi.org/10.1126/sciadv.abd5046