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Androgen Receptor Activation in Glioblastoma Can Be Achieved by Ligand-Independent Signaling through EGFR—A Potential Therapeutic Target

Androgen receptor (AR) is a ligand-mediated transcription factor that belongs to the superfamily of steroid receptors. AR is overexpressed in most glioblastomas and is a potential therapeutic target. In prostate and breast cancers, AR activation can be achieved also by a ligand-independent signaling...

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Detalles Bibliográficos
Autores principales: Zalcman, Nomi, Gutreiman, Mijal, Shahar, Tal, Weller, Michael, Lavon, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535837/
https://www.ncbi.nlm.nih.gov/pubmed/34681618
http://dx.doi.org/10.3390/ijms222010954