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Gene Amplification and the Extrachromosomal Circular DNA
Oncogene amplification is closely linked to the pathogenesis of a broad spectrum of human malignant tumors. The amplified genes localize either to the extrachromosomal circular DNA, which has been referred to as cytogenetically visible double minutes (DMs), or submicroscopic episome, or to the chrom...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535887/ https://www.ncbi.nlm.nih.gov/pubmed/34680928 http://dx.doi.org/10.3390/genes12101533 |