Improved SNV Discovery in Barcode-Stratified scRNA-seq Alignments

Currently, the detection of single nucleotide variants (SNVs) from 10 x Genomics single-cell RNA sequencing data (scRNA-seq) is typically performed on the pooled sequencing reads across all cells in a sample. Here, we assess the gaining of information regarding SNV assessments from individual cell s...

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Detalles Bibliográficos
Autores principales: N. M., Prashant, Liu, Hongyu, Dillard, Christian, Ibeawuchi, Helen, Alsaeedy, Turkey, Chan, Hang, Horvath, Anelia Dafinova
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535975/
https://www.ncbi.nlm.nih.gov/pubmed/34680953
http://dx.doi.org/10.3390/genes12101558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535975/
https://www.ncbi.nlm.nih.gov/pubmed/34680953
http://dx.doi.org/10.3390/genes12101558

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