Receptor-Loaded Virion Endangers GPCR Signaling: Mechanistic Exploration of SARS-CoV-2 Infections and Pharmacological Implications

SARS-CoV-2 exploits the respiratory tract epithelium including lungs as the primary entry point and reaches other organs through hematogenous expansion, consequently causing multiorgan injury. Viral E protein interacts with cell junction-associated proteins PALS1 or ZO-1 to gain massive penetration...

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Detalles Bibliográficos
Autores principales: Zhang, Qiangmin, Friedman, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535999/
https://www.ncbi.nlm.nih.gov/pubmed/34681624
http://dx.doi.org/10.3390/ijms222010963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535999/
https://www.ncbi.nlm.nih.gov/pubmed/34681624
http://dx.doi.org/10.3390/ijms222010963

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