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Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma

Increasing the level of reactive oxygen species (ROS) in cancer cells has been suggested as a viable approach to cancer therapy. Our previous study has demonstrated that mitochondria-targeted flavone-naphthalimide-polyamine conjugate 6c elevates the level of ROS in cancer cells. However, the detaile...

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Detalles Bibliográficos
Autores principales: Wang, Senzhen, Xu, Xiaojuan, Che, Delu, Fan, Ronghui, Gao, Mengke, Cao, Yue, Ge, Chaochao, Feng, Yongli, Li, Jinghua, Xie, Songqiang, Wang, Chaojie, Dai, Fujun, Gao, Lei, Wang, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536041/
https://www.ncbi.nlm.nih.gov/pubmed/34681647
http://dx.doi.org/10.3390/ijms222010987