Cargando…
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma
Increasing the level of reactive oxygen species (ROS) in cancer cells has been suggested as a viable approach to cancer therapy. Our previous study has demonstrated that mitochondria-targeted flavone-naphthalimide-polyamine conjugate 6c elevates the level of ROS in cancer cells. However, the detaile...
Autores principales: | Wang, Senzhen, Xu, Xiaojuan, Che, Delu, Fan, Ronghui, Gao, Mengke, Cao, Yue, Ge, Chaochao, Feng, Yongli, Li, Jinghua, Xie, Songqiang, Wang, Chaojie, Dai, Fujun, Gao, Lei, Wang, Yuxia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536041/ https://www.ncbi.nlm.nih.gov/pubmed/34681647 http://dx.doi.org/10.3390/ijms222010987 |
Ejemplares similares
-
The Role of p53-Mediated Signaling in the Therapeutic Response of Colorectal Cancer to 9F, a Spermine-Modified Naphthalene Diimide Derivative
por: Gao, Lei, et al.
Publicado: (2020) -
Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma
por: Ge, Chaochao, et al.
Publicado: (2017) -
Design, Synthesis, and Biological Evaluation of Benzo[cd]indol-2(1H)-ones Derivatives as a Lysosome-Targeted Anti-metastatic Agent
por: Li, Jinghua, et al.
Publicado: (2021) -
Inhibition of autophagic-lysosomal delivery and autophagic lactolysis by asparagine
Publicado: (1991) -
Triamterene induces autophagic degradation of lysosome by exacerbating lysosomal integrity
por: Park, Na Yeon, et al.
Publicado: (2021)