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Therapeutic Effect of an Antibody-Derived Peptide in a Galleria mellonella Model of Systemic Candidiasis

The synthetic peptide T11F (TCRVDHRGLTF), with sequence identical to a fragment of the constant region of human IgM, and most of its alanine-substituted derivatives proved to possess a significant candidacidal activity in vitro. In this study, the therapeutic efficacy of T11F, D5A, the derivative mo...

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Detalles Bibliográficos
Autores principales: Ottaviano, Emerenziana, Borghi, Elisa, Giovati, Laura, Falleni, Monica, Tosi, Delfina, Magliani, Walter, Morace, Giulia, Conti, Stefania, Ciociola, Tecla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536055/
https://www.ncbi.nlm.nih.gov/pubmed/34681564
http://dx.doi.org/10.3390/ijms222010904