Marek’s Disease Virus Telomeric Integration Profiles of Neoplastic Host Tissues Reveal Unbiased Chromosomal Selection and Loss of Cellular Diversity during Tumorigenesis

The avian α-herpesvirus known as Marek’s disease virus (MDV) linearly integrates its genomic DNA into host telomeres during infection. The resulting disease, Marek’s disease (MD), is characterized by virally-induced lymphomas with high mortality. The temporal dynamics of MDV-positive (MDV(+)) transf...

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Detalles Bibliográficos
Autores principales: Glass, Marla C., Smith, Justin M., Cheng, Hans H., Delany, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536068/
https://www.ncbi.nlm.nih.gov/pubmed/34681024
http://dx.doi.org/10.3390/genes12101630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536068/
https://www.ncbi.nlm.nih.gov/pubmed/34681024
http://dx.doi.org/10.3390/genes12101630

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