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Amino acids activate mTORC1 to release roe deer embryos from decelerated proliferation during diapause

Embryonic diapause in mammals leads to a reversible developmental arrest. While completely halted in many species, European roe deer (Capreolus capreolus) embryos display a continuous deceleration of proliferation. During a 4-mo period, the cell doubling time is 2 to 3 wk. During this period, the pr...

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Detalles Bibliográficos
Autores principales: van der Weijden, Vera A., Bick, Jochen T., Bauersachs, Stefan, Rüegg, Anna B., Hildebrandt, Thomas B., Goeritz, Frank, Jewgenow, Katarina, Giesbertz, Pieter, Daniel, Hannelore, Derisoud, Emilie, Chavatte-Palmer, Pascale, Bruckmaier, Rupert M., Drews, Barbara, Ulbrich, Susanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536382/
https://www.ncbi.nlm.nih.gov/pubmed/34452997
http://dx.doi.org/10.1073/pnas.2100500118