Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells

Tanshinone IIa (TanIIa), an ingredient of Radix Salviae Miltiorrhizae, has an anticancer effect on various solid tumors with high efficiency and low toxicity. Nonetheless, the underlying role of TanIIa in acute promyelocytic leukemia (APL) remains unclear. Here, we revealed that TanIIa drastically i...

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Detalles Bibliográficos
Autores principales: Pan, Yiming, Chen, Lingyan, Li, Ruibai, Liu, Yu, Nan, Mengdie, Hou, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536410/
https://www.ncbi.nlm.nih.gov/pubmed/34691211
http://dx.doi.org/10.1155/2021/3372403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536410/
https://www.ncbi.nlm.nih.gov/pubmed/34691211
http://dx.doi.org/10.1155/2021/3372403

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