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Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
In parasite and viral infections, aberrant B cell responses can suppress germinal center reactions thereby blunting long-lived memory and may provoke immunopathology including autoimmunity. Using COVID-19 as model, we set out to identify serological, cellular, and transcriptomic imprints of patholog...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536484/ https://www.ncbi.nlm.nih.gov/pubmed/34723157 http://dx.doi.org/10.1016/j.isci.2021.103325 |