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Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19

In parasite and viral infections, aberrant B cell responses can suppress germinal center reactions thereby blunting long-lived memory and may provoke immunopathology including autoimmunity. Using COVID-19 as model, we set out to identify serological, cellular, and transcriptomic imprints of patholog...

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Detalles Bibliográficos
Autores principales: Schultheiß, Christoph, Paschold, Lisa, Willscher, Edith, Simnica, Donjete, Wöstemeier, Anna, Muscate, Franziska, Wass, Maxi, Eisenmann, Stephan, Dutzmann, Jochen, Keyßer, Gernot, Gagliani, Nicola, Binder, Mascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536484/
https://www.ncbi.nlm.nih.gov/pubmed/34723157
http://dx.doi.org/10.1016/j.isci.2021.103325

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