Cargando…
Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
In parasite and viral infections, aberrant B cell responses can suppress germinal center reactions thereby blunting long-lived memory and may provoke immunopathology including autoimmunity. Using COVID-19 as model, we set out to identify serological, cellular, and transcriptomic imprints of patholog...
Autores principales: | Schultheiß, Christoph, Paschold, Lisa, Willscher, Edith, Simnica, Donjete, Wöstemeier, Anna, Muscate, Franziska, Wass, Maxi, Eisenmann, Stephan, Dutzmann, Jochen, Keyßer, Gernot, Gagliani, Nicola, Binder, Mascha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536484/ https://www.ncbi.nlm.nih.gov/pubmed/34723157 http://dx.doi.org/10.1016/j.isci.2021.103325 |
Ejemplares similares
-
Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination
por: Paschold, Lisa, et al.
Publicado: (2022) -
Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21(R110) chronic lymphocytic leukemia
por: Paschold, Lisa, et al.
Publicado: (2022) -
Azacitidine-induced reconstitution of the bone marrow T cell repertoire is associated with superior survival in AML patients
por: Grimm, Juliane, et al.
Publicado: (2022) -
PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition
por: Claaß, Luise Victoria, et al.
Publicado: (2022) -
Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts
por: Simnica, Donjete, et al.
Publicado: (2021)