Compartment-specific metabolome labeling enables the identification of subcellular fluxes that may serve as promising metabolic engineering targets in CHO cells

(13)C labeling data are used to calculate quantitative intracellular flux patterns reflecting in vivo conditions. Given that approaches for compartment-specific metabolomics exist, the benefits they offer compared to conventional non-compartmented (13)C flux studies remain to be determined. Using co...

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Detalles Bibliográficos
Autores principales: Wijaya, Andy Wiranata, Ulmer, Andreas, Hundsdorfer, Lara, Verhagen, Natascha, Teleki, Attila, Takors, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536584/
https://www.ncbi.nlm.nih.gov/pubmed/34590184
http://dx.doi.org/10.1007/s00449-021-02628-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536584/
https://www.ncbi.nlm.nih.gov/pubmed/34590184
http://dx.doi.org/10.1007/s00449-021-02628-1

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