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Enigmatic mechanism of the N-vinylpyrrolidone hepatocarcinogenicity in the rat

N-vinyl pyrrolidone (NVP) is produced up to several thousand tons per year as starting material for the production of polymers to be used in pharmaceutics, cosmetics and food technology. Upon inhalation NVP was carcinogenic in the rat, liver tumor formation is starting already at the rather low conc...

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Detalles Bibliográficos
Autores principales: Oesch, Franz, Fruth, Daniela, Hengstler, Jan G., Fabian, Eric, Berger, Franz Ingo, Landsiedel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536644/
https://www.ncbi.nlm.nih.gov/pubmed/34595563
http://dx.doi.org/10.1007/s00204-021-03151-8