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Enigmatic mechanism of the N-vinylpyrrolidone hepatocarcinogenicity in the rat
N-vinyl pyrrolidone (NVP) is produced up to several thousand tons per year as starting material for the production of polymers to be used in pharmaceutics, cosmetics and food technology. Upon inhalation NVP was carcinogenic in the rat, liver tumor formation is starting already at the rather low conc...
Autores principales: | Oesch, Franz, Fruth, Daniela, Hengstler, Jan G., Fabian, Eric, Berger, Franz Ingo, Landsiedel, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536644/ https://www.ncbi.nlm.nih.gov/pubmed/34595563 http://dx.doi.org/10.1007/s00204-021-03151-8 |
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