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The flashfm approach for fine-mapping multiple quantitative traits

Joint fine-mapping that leverages information between quantitative traits could improve accuracy and resolution over single-trait fine-mapping. Using summary statistics, flashfm (flexible and shared information fine-mapping) fine-maps signals for multiple traits, allowing for missing trait measureme...

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Detalles Bibliográficos
Autores principales: Hernández, N., Soenksen, J., Newcombe, P., Sandhu, M., Barroso, I., Wallace, C., Asimit, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536717/
https://www.ncbi.nlm.nih.gov/pubmed/34686674
http://dx.doi.org/10.1038/s41467-021-26364-y