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JWA suppresses proliferation in trastuzumab-resistant breast cancer by downregulating CDK12

Breast cancer is the most common cancer worldwide. JWA is a microtubule-associated protein that has been identified as a tumor suppressor, and its downregulation in tumors is an independent adverse prognostic factor. The objective of this study was to explore the expression, regulation, and mechanis...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Qian, Chao, Xie, Yinghong, Huang, Xiang, Chen, Junjie, Ren, Yanlin, Fu, Ziyi, Li, Yongfei, Zeng, Tianyu, Yang, Fan, Zhou, Jianwei, Li, Wei, Yin, Yongmei, Wang, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536718/
https://www.ncbi.nlm.nih.gov/pubmed/34686673
http://dx.doi.org/10.1038/s41420-021-00693-9