Cargando…
JWA suppresses proliferation in trastuzumab-resistant breast cancer by downregulating CDK12
Breast cancer is the most common cancer worldwide. JWA is a microtubule-associated protein that has been identified as a tumor suppressor, and its downregulation in tumors is an independent adverse prognostic factor. The objective of this study was to explore the expression, regulation, and mechanis...
Autores principales: | Liang, Yan, Qian, Chao, Xie, Yinghong, Huang, Xiang, Chen, Junjie, Ren, Yanlin, Fu, Ziyi, Li, Yongfei, Zeng, Tianyu, Yang, Fan, Zhou, Jianwei, Li, Wei, Yin, Yongmei, Wang, Changqing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536718/ https://www.ncbi.nlm.nih.gov/pubmed/34686673 http://dx.doi.org/10.1038/s41420-021-00693-9 |
Ejemplares similares
-
JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling
por: Ren, Yanlin, et al.
Publicado: (2021) -
JWA suppresses the invasion of human breast carcinoma cells by downregulating the expression of CXCR4
por: Xu, Lingyun, et al.
Publicado: (2018) -
JAC1 targets YY1 mediated JWA/p38 MAPK signaling to inhibit proliferation and induce apoptosis in TNBC
por: Zhai, Zurong, et al.
Publicado: (2022) -
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer
por: Liu, Xin, et al.
Publicado: (2012) -
Targeting JWA for Cancer Therapy: Functions, Mechanisms and Drug Discovery
por: Ding, Kun, et al.
Publicado: (2022)