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Salivary gland extract from the deer tick, Ixodes scapularis, facilitates neuroinvasion by Powassan virus in BALB/c mice

Powassan virus (POWV) is a neuroinvasive flavivirus transmitted to mammals by the bite of ixodid ticks. In this study, we sought to investigate the impact of tick salivary gland extract (SGE) on POWV neuroinvasion. BALB/c mice were footpad inoculated with either a high dose or a low dose of POWV, wi...

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Detalles Bibliográficos
Autores principales: Santos, Rodrigo I., Hermance, Meghan E., Reynolds, Erin S., Thangamani, Saravanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536725/
https://www.ncbi.nlm.nih.gov/pubmed/34686683
http://dx.doi.org/10.1038/s41598-021-00021-2