Activation of the adipocyte CREB/CRTC pathway in obesity

Obesity is a major risk factor for the development of type II diabetes. Increases in adipose tissue mass trigger insulin resistance via the release of pro-inflammatory cytokines from adipocytes and macrophages. CREB and the CRTC coactivators have been found to promote insulin resistance in obesity,...

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Detalles Bibliográficos
Autores principales: Yoon, Young-Sil, Liu, Weiyi, Van de Velde, Sam, Matsumura, Shigenobu, Wiater, Ezra, Huang, Ling, Montminy, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536733/
https://www.ncbi.nlm.nih.gov/pubmed/34686752
http://dx.doi.org/10.1038/s42003-021-02735-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536733/
https://www.ncbi.nlm.nih.gov/pubmed/34686752
http://dx.doi.org/10.1038/s42003-021-02735-5

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