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Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells

The corneal epithelium is consistently regenerated by limbal stem/progenitor cells (LSCs), a very small population of adult stem cells residing in the limbus. Several Wnt ligands, including Wnt6, are preferentially expressed in the limbus. To investigate the role of Wnt6 in regulating proliferation...

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Detalles Bibliográficos
Autores principales: Bonnet, Clémence, Oh, Denise, Mei, Hua, Robertson, Sarah, Chang, Derek, Bourges, Jean-Louis, Behar-Cohen, Francine, Zheng, Jie J., Deng, Sophie X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536737/
https://www.ncbi.nlm.nih.gov/pubmed/34686698
http://dx.doi.org/10.1038/s41598-021-00273-y